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PRSS2 Rabbit Polyclonal Antibody

CAT: 0992-HA500182Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500182Size:100 µL
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Description
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Product Name Alternative
Anionic trypsinogen antibody EC 3.4.21.4 antibody MGC111183 antibody MGC120174 antibody Protease serine 2 preproprotein antibody Protease, serine, 2 (trypsin 2) antibody Protease, serine, 2 antibody Protease, serine, 2, preproprotein antibody Prss2 antibody Serine protease 2 antibody TRY2 antibody TRY2_HUMAN antibody TRY8 antibody TRYP2 antibody Trypsin 2 antibody Trypsin II antibody Trypsin-2 antibody Trypsinogen 2 antibody
Abbreviation
PRSS2
Swiss Prot
P07478 Human, P07146 Mouse, P00763 Rat
Cellular Locus
Extracellular space.
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein within human PRSS2 aa 1-120.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Human small intestine tissue lysates, rat pancreas tissue, human pancreas tissue, mouse pancreas tissue, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:200-1:1,000;IF-Cell: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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