PRSS2 Rabbit Polyclonal Antibody

PRSS2 Rabbit Polyclonal Antibody

• Description: This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
• Product Name Alternative: Anionic trypsinogen antibody EC 3.4.21.4 antibody MGC111183 antibody MGC120174 antibody Protease serine 2 preproprotein antibody Protease, serine, 2 (trypsin 2) antibody Protease, serine, 2 antibody Protease, serine, 2, preproprotein antibody Prss2 antibody Serine protease 2 antibody TRY2 antibody TRY2_HUMAN antibody TRY8 antibody TRYP2 antibody Trypsin 2 antibody Trypsin II antibody Trypsin-2 antibody Trypsinogen 2 antibody
• Abbreviation: PRSS2
• CAS Number: 9007-83-4
• Swiss Prot: P07478 Human, P07146 Mouse, P00763 Rat
• Cellular Locus: Extracellular space.
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse
• Immunogen: Recombinant protein within human PRSS2 aa 1-120.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P, IF-Cell
• Positive Control: Human small intestine tissue lysates, rat pancreas tissue, human pancreas tissue, mouse pancreas tissue, SH-SY5Y.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000;IHC-P: 1:200-1:1,000;IF-Cell: 1:50-1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 26 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No