ATR Rabbit Polyclonal Antibody

ATR Rabbit Polyclonal Antibody

• Description: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
• Product Name Alternative: Ataxia telangiectasia and Rad3 related antibody Ataxia telangiectasia and Rad3-related protein antibody ATR antibody ATR_HUMAN antibody FCTCS antibody FRAP Related Protein 1 antibody FRAP-related protein 1 antibody FRP1 antibody MEC1 antibody MEC1 mitosis entry checkpoint 1 homolog antibody Protein kinase ATR antibody RAC3 antibody Rad3 related protein antibody SCKL antibody SCKL1 antibody Serine/threonine protein kinase ATR antibody Serine/threonine-protein kinase ATR antibody
• Abbreviation: ATR
• CAS Number: 9007-83-4
• Swiss Prot: Q13535 Human, D3Z822 Rat
• Cellular Locus: Nucleus, PML body, Chromosome.
• Host: Rabbit
• Species Reactivity: Human, Rat
• Immunogen: Recombinant protein within human aa 1198-1410.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P
• Positive Control: Hela cell lysates, rat large intestine tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 301 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No