Spry2 Rabbit Polyclonal Antibody

Spry2 Rabbit Polyclonal Antibody

• Description: This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
• Product Name Alternative: hSPRY 2 antibody hSPRY2 antibody MGC23039 antibody Protein sprouty homolog 2 antibody Sprouty 2 antibody Sprouty homolog 2 (Drosophila) antibody Sprouty homolog 2 antibody Sprouty2 antibody Spry 2 antibody Spry-2 antibody SPRY2 antibody SPY2_HUMAN antibody
• Abbreviation: SPRY2
• CAS Number: 9007-83-4
• Swiss Prot: O43597 Human,
• Cellular Locus: Ruffle membrane, cytoskeleton.
• Host: Rabbit
• Species Reactivity: Human, Rat
• Immunogen: Recombinant protein within human Spry2 aa 1-180.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P
• Positive Control: Rat liver tissue lysates, human liver tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500 ;IHC-P: 1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 35 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No