Spry2 Rabbit Polyclonal Antibody

CAT: 0992-HA500170Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-HA500170Size:100 µL
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Description
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
CAS Number
9007-83-4
Product Name Alternative
hSPRY 2 antibody hSPRY2 antibody MGC23039 antibody Protein sprouty homolog 2 antibody Sprouty 2 antibody Sprouty homolog 2 (Drosophila) antibody Sprouty homolog 2 antibody Sprouty2 antibody Spry 2 antibody Spry-2 antibody SPRY2 antibody SPY2_HUMAN antibody
Abbreviation
SPRY2
Swiss Prot
O43597 Human,
Cellular Locus
Ruffle membrane, cytoskeleton.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human Spry2 aa 1-180.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Rat liver tissue lysates, human liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 35 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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