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mGluR6 Rabbit Polyclonal Antibody

CAT: 0992-HA500158Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500158Size:100 µL
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Description
mGluR6 is specifically expressed in the retina, in a subtype of bipolar cells that depolarize in response to light, known as ON bipolar cells. These cells form synapses with photoreceptor cells, and detect the neurotransmitter glutamate via a GPCR signal transduction cascade. The glutamate receptor mGluR6 is located post-synaptically at the tips of the bipolar cell dendrites, and is responsible for initiating a signaling cascade that ultimately controls gating of the TRPM1 channel. In human patients, mutations in the GRM6 gene are associated with congenital stationary night blindness.
CAS Number
9007-83-4
Product Name Alternative
CSNB1B antibody DKFZp686H1993 antibody GluR6 antibody Glutamate receptor metabotropic 6 antibody GPRC1F antibody Grm6 antibody GRM6_HUMAN antibody Metabotropic glutamate receptor 6 antibody mGlu6 antibody mGluR6 antibody
Abbreviation
Metabotropic glutamate receptor 6 mGluR6
Swiss Prot
O15303 Human
Cellular Locus
Cell membrane, Cell projection, Endoplasmic reticulum, Golgi apparatus, Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human mGluR6 aa 820-877.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
HepG2 cell lysates, SHSY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 95 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No