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GNB3 Rabbit Polyclonal Antibody

CAT: 0992-HA500153Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500153Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Heterotrimeric guanine nucleotide-binding proteins ( G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.
CAS Number
9007-83-4
Product Name Alternative
G protein beta 3 subunit antibody GBB3_HUMAN antibody GNB3 antibody GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 antibody GTP binding regulatory protein beta 3 chain antibody Guanine nucleotide binding protein (G protein) beta polypeptide 3 antibody Guanine nucleotide binding protein G antibody Guanine nucleotide binding protein G (I)/G (S)/G (T) beta subunit 3 antibody Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-3 antibody Hypertension associated protein antibody IG antibody SG antibody Transducin beta chain 3 antibody Tsubunit beta 3 antibody
Abbreviation
Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-3 Transducin beta chain 3
Swiss Prot
P16520 Human, Q61011 Mouse, P52287 Rat
Cellular Locus
Cytosol.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human GNB3 aa 10-60.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
HepG2 cell lysate, Hela cell lysate, mouse brain tissue lysate, human brain tissue lysate, rat brain tissue lysate, rat kidney tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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