ASIC4 Rabbit Polyclonal Antibody

• Description:

  This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.

• Product Name Alternative:

  Acid-sensing ion channel 4 ASIC4 Amiloride-sensitive cation channel 4 Amiloride-sensitive cation channel 4, pituitary ACCN4

• Abbreviation:

  ASIC4

• Swiss Prot:

  Q96FT7 Human, Q7TNS7 Mouse, Q9JHS6 Rat

• Cellular Locus:

  Membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human ASIC4 aa 250-450.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IHC-P, FC

• Positive Control:

  HepG2 cell lysate, human brain tissue lysate, K562 cell lysate, rat brain tissue, mouse pituitary tissue, SH-SY5Y.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000-1:2,000 ;IHC-P: 1:100-1:500 ;FC: 1:100-1:500

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  70 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4