GNB3 Rabbit Polyclonal Antibody

CAT: 0992-HA500127Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-HA500127Size:100 µL
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Description
Heterotrimeric guanine nucleotide-binding proteins ( G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.
CAS Number
9007-83-4
Product Name Alternative
G protein beta 3 subunit antibody GBB3_HUMAN antibody GNB3 antibody GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 antibody GTP binding regulatory protein beta 3 chain antibody Guanine nucleotide binding protein (G protein) beta polypeptide 3 antibody Guanine nucleotide binding protein G antibody Guanine nucleotide binding protein G (I)/G (S)/G (T) beta subunit 3 antibody Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-3 antibody Hypertension associated protein antibody IG antibody SG antibody Transducin beta chain 3 antibody Tsubunit beta 3 antibody
Abbreviation
Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-3 Transducin beta chain 3
Swiss Prot
P16520 Human, Q61011 Mouse, P52287 Rat
Cellular Locus
Cytosol, Extracellular region or secreted, Plasma Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human GNB3 aa 100-150.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HepG2 cell lysate, A549 cell lysate, mouse kidney tissue lysate, rat brian tissue lysate, F9, rat kidney tissue, mouse brian tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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