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MCRS1 Rabbit Polyclonal Antibody

CAT: 0992-HA500120Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500120Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MSP58, also known as MCRS1 (microspherule protein 1), P78 or INO80Q, is a 462 amino acid protein that localizes to the nucleus and contains one FHA domain. Expressed at high levels during the S phase of the cell cycle and present in testis, prostate, thymus, spleen and colon, MSP58 functions to modulate the transcriptional activity of Daxx (a transcriptional repressor) by recruiting Daxx to the nucleolus. Additionally, MSP58 may play a role in the inhibition of TERT telomerase activity, further implicating MSP58 as an important protein in transcriptional regulation. The gene encoding MSP58 maps to human chromosome 12 and is expressed as multiple alternatively spliced isoforms. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome and is associated wirh hypochondrogenesis, achondrogenesis and Kniest dysplasia.
CAS Number
9007-83-4
Product Name Alternative
58 kDa microspherule protein antibody Cell cycle regulated factor (78 kDa) antibody Cell cycle regulated factor p78 antibody Cell cycle-regulated factor p78 antibody ICP22BP antibody INO80 complex subunit J antibody MCRS 1 antibody MCRS 2 antibody MCRS1 antibody MCRS1_HUMAN antibody MCRS2 antibody Microspherule protein 1 antibody MSP 58 antibody MSP58 antibody p78 antibody
Abbreviation
MCRS1
Swiss Prot
Q96EZ8 Human, Q99L90 Mouse, G3V9E0 Rat
Cellular Locus
Nucleus, Nucleolus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human MCRS1 aa 1-200.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
SH-SY5Y cell lysates, rat large intestine tissue, human liver tissue, human pancreas tissue, mouse testis tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No