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CD66b Rabbit Polyclonal Antibody

CAT: 0992-HA500100Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500100Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carcinoembryonic antigen-related cell adhesion molecule 8, also designated CD67, CD66b or nonspecific cross-reacting antigen (NCA-95), belongs to the human carcinoembryonic antigen (CEA) family. The CD67 antigen is encoded by the CEACAM8 (CGM6) gene, which is exclusively expressed in neutrophils and eosinophils. In neutrophils, the CEACAM8 gene is primarily detected in the secondary granules within the cytoplasm, but it can also be found in lower amounts on the plasma membrane. The amount of CD67 on the plasma membrane is up-regulated upon granulocyte activation. CD67 has been located on the surface of neutrophilic and eosinophilic granulocytes at late stages of differentiation. It exhibits heterophilic cell adhesion properties with CD66c, which is coexpressed with CD67 in granulocytes. CD67, which is attached to the membrane by a GPI-anchor, is expressed in leukocytes of chronic myeloid leukemia patients and bone marrow and in granulocytes in the spleen, thymus and lungs.
CAS Number
9007-83-4
Product Name Alternative
Carcinoembryonic antigen CGM6 antibody Carcinoembryonic antigen gene family member 6 antibody Carcinoembryonic antigen related cell adhesion molecule 8 antibody Carcinoembryonic antigen-related cell adhesion molecule 8 antibody CD 66b antibody CD 67 antibody CD66b antibody CD66b antigen antibody CD67 antibody CD67 antigen antibody CEACAM 8 antibody CEACAM8 antibody CEAM8_HUMAN antibody CGM 6 antibody CGM6 antibody NCA 95 antibody NCA95 antibody Non-specific cross-reacting antigen NCA-95 antibody Nonspecific cross reacting antigen NCA 95 antibody Nonspecific cross reacting antigen NCA95 antibody
Abbreviation
CEACAM8
Swiss Prot
P31997 Human
Cellular Locus
Cell membrane, Cell surface.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human CD66b aa 1-250.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, mIHC, IF-Tissue
Positive Control
Human cervical cancer, human colon cancer tissue, human breast cancer tissue, human spleen tissue, human colon tissue, U937 cell lysate, A431 cell lysate, Daudi cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:1,000 ;mIHC: 1:1,000 ;IF-Tissue: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 38 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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