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AMPS Rabbit Polyclonal Antibody

CAT: 0992-HA500092Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500092Size:100 µL
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Description
Adenylosuccinate lyase (ASL) is an enzyme that catalyzes two reactions in the de novo purine biosynthetic pathway. In both reactions it uses an E1cb elimination reaction mechanism to cleave fumarate off of the substrate. In the first reaction, ASL converts 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR) to 5-aminoimidazole-4-carboxamide ribotide (AICAR) and fumarate. AICAR proceeds through three more reactions before it becomes adenylosuccinate (also called succinyladenosine monophosphate or SAMP), which ASL then splits into adenosine monophosphate (AMP) and fumarate. ASL is important to cells not only because of its involvement in creating purines needed for cellular replication, but also because it helps regulate metabolic processes by controlling the levels of AMP and fumarate in the cell.
CAS Number
9007-83-4
Product Name Alternative
Adenylosuccinase antibody Adenylosuccinate lyase antibody ADSL antibody AMPS antibody ASase antibody ASL antibody OTTHUMP00000199172 antibody OTTHUMP00000199173 antibody PUR8_HUMAN antibody
Abbreviation
Adenylosuccinate lyase1 Publication ADSL1 Publication ASL Adenylosuccinase1 Publication ASase
Swiss Prot
P30566 Human, P54822 Mouse
Cellular Locus
Cytosol.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within N-terminal human AMPS.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Jurkatcell lysate, NIH/3T3 cell lysate, mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
54 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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