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ACVR2A Rabbit Polyclonal Antibody

CAT: 0992-HA500084Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500084Size:100 µL
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Description
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
CAS Number
9007-83-4
Product Name Alternative
Activin A receptor type IIA antibody Activin receptor type 2A antibody Activin receptor type IIA antibody Activin receptor type-2A antibody ACTR 2 antibody ACTR IIA antibody ACTR-IIA antibody ACTR2 antibody ACTRII antibody ACTRIIA antibody Acvr 2 antibody Acvr 2A antibody Acvr2 antibody ACVR2A antibody AVR2A_HUMAN antibody OTTHUMP00000197918 antibody
Abbreviation
Activin receptor type-2A Activin receptor type IIA ACTR-IIA ACTRIIA
Swiss Prot
P27037 Human, P27038 Mouse, P38444 Rat
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human ACVR2A aa 470-513.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
SW480 cell lysate, K562 cell lysate, HepG2 cell lysate, mouse kidney tissue lysate, mouse testis tissue lysate, rat testis tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size:58 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No