ACVR2A Rabbit Polyclonal Antibody

ACVR2A Rabbit Polyclonal Antibody

• Description: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
• Product Name Alternative: Activin A receptor type IIA antibody Activin receptor type 2A antibody Activin receptor type IIA antibody Activin receptor type-2A antibody ACTR 2 antibody ACTR IIA antibody ACTR-IIA antibody ACTR2 antibody ACTRII antibody ACTRIIA antibody Acvr 2 antibody Acvr 2A antibody Acvr2 antibody ACVR2A antibody AVR2A_HUMAN antibody OTTHUMP00000197918 antibody
• Abbreviation: Activin receptor type-2A Activin receptor type IIA ACTR-IIA ACTRIIA
• CAS Number: 9007-83-4
• Swiss Prot: P27037 Human, P27038 Mouse, P38444 Rat
• Cellular Locus: Membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human ACVR2A aa 470-513.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB
• Positive Control: SW480 cell lysate, K562 cell lysate, HepG2 cell lysate, mouse kidney tissue lysate, mouse testis tissue lysate, rat testis tissue lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size:58 kDa.
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No