ACVR2A Rabbit Polyclonal Antibody

• Description:

  This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

• Product Name Alternative:

  Activin A receptor type IIA antibody Activin receptor type 2A antibody Activin receptor type IIA antibody Activin receptor type-2A antibody ACTR 2 antibody ACTR IIA antibody ACTR-IIA antibody ACTR2 antibody ACTRII antibody ACTRIIA antibody Acvr 2 antibody Acvr 2A antibody Acvr2 antibody ACVR2A antibody AVR2A_HUMAN antibody OTTHUMP00000197918 antibody

• Abbreviation:

  Activin receptor type-2A Activin receptor type IIA ACTR-IIA ACTRIIA

• Swiss Prot:

  P27037 Human, P27038 Mouse, P38444 Rat

• Cellular Locus:

  Membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide within human ACVR2A aa 470-513.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB

• Positive Control:

  SW480 cell lysate, K562 cell lysate, HepG2 cell lysate, mouse kidney tissue lysate, mouse testis tissue lysate, rat testis tissue lysate.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:1,000

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size:58 kDa.

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4