PPP1CA Rabbit Polyclonal Antibody

• Description:

  The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Product Name Alternative:

  Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit antibody Catalytic subunit antibody EC 3.1.3.16 antibody MGC15877 antibody MGC1674 antibody PP 1A antibody PP-1A antibody PP1A antibody PP1A_HUMAN antibody PP1alpha antibody PP2C ALPHA antibody PP2CA antibody Ppp1ca antibody Protein Phosphatase 2C Alpha Isoform antibody Serine threonine protein phosphatase PP1 alpha catalytic subunit antibody Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1 antibody Serine/threonine-protein phosphatase PP1-alpha catalytic subunit antibody

• Abbreviation:

  PPP1CA

• Swiss Prot:

  P62136 Human, P62137 Mouse, P62138 Rat

• Cellular Locus:

  Nucleus, nucleoplasm, nucleolus, cytoplasm.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide within human PPP1CA aa 291-330.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IHC-P

• Positive Control:

  MCF-7 cell lysate, A549 cell lysate, K562 cell lysate, Hela cell lysate, rat brain tissue lysate, mouse brain tissue lysate, rat large intestine tissue, mouse kidney tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  38 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4