PPP1CA Rabbit Polyclonal Antibody

CAT: 0992-HA500074Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-HA500074Size:100 µL
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Description
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Product Name Alternative
Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit antibody Catalytic subunit antibody EC 3.1.3.16 antibody MGC15877 antibody MGC1674 antibody PP 1A antibody PP-1A antibody PP1A antibody PP1A_HUMAN antibody PP1alpha antibody PP2C ALPHA antibody PP2CA antibody Ppp1ca antibody Protein Phosphatase 2C Alpha Isoform antibody Serine threonine protein phosphatase PP1 alpha catalytic subunit antibody Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1 antibody Serine/threonine-protein phosphatase PP1-alpha catalytic subunit antibody
Abbreviation
PPP1CA
Swiss Prot
P62136 Human, P62137 Mouse, P62138 Rat
Cellular Locus
Nucleus, nucleoplasm, nucleolus, cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human PPP1CA aa 291-330.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
MCF-7 cell lysate, A549 cell lysate, K562 cell lysate, Hela cell lysate, rat brain tissue lysate, mouse brain tissue lysate, rat large intestine tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
38 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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