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GAMT Rabbit Polyclonal Antibody

CAT: 0992-HA500071Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500071Size:100 µL
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Description
Guanidinoacetate N-methyltransferase (EC 2.1.1.2) is an enzyme that catalyzes the chemical reaction and is encoded by gene GAMT located on chromosome 19p13.3.This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase. Other names in common use include GA methylpherase, guanidinoacetate methyltransferase, guanidinoacetate transmethylase, methionine-guanidinoacetic transmethylase, and guanidoacetate methyltransferase. This enzyme participates in glycine, serine and threonine metabolism and arginine and proline metabolism.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.
CAS Number
9007-83-4
Product Name Alternative
CCDS2 antibody Epididymis secretory protein Li 20 antibody GAMT antibody GAMT_HUMAN antibody Guanidinoacetate N methyltransferase antibody Guanidinoacetate N-methyltransferase antibody HEL-S-20 antibody PIG2 antibody TP53I2 antibody
Abbreviation
GAMT Guanidinoacetate N-methyltransferase (EC:2.1.1.2)
Swiss Prot
Q14353 Human, O35969 Mouse, P10868 Rat
Cellular Locus
Cytosol,nucleus,cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human GAMT aa 1-222.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Hela cell lysate, mouse liver tissue lysate, rat liver tissue lysate, rat kidney tissue, human liver tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P:1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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