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SMURF1 Rabbit Polyclonal Antibody

CAT: 0992-HA500057Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500057Size:100 µL
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Description
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS . Plays a role in dendrite formation by melanocytes .
CAS Number
9007-83-4
Product Name Alternative
E3 ubiquitin-protein ligase SMURF1 antibody hSMURF1 antibody KIAA1625 antibody Smad specific E3 ubiquitin ligase 1 antibody SMAD specific E3 ubiquitin protein ligase 1 antibody Smad ubiquitination regulatory factor 1 antibody SMAD-specific E3 ubiquitin-protein ligase 1 antibody SMUF1_HUMAN antibody SMURF 1 antibody smurf1 antibody
Abbreviation
3 ubiquitin-protein ligase SMURF1 hSMURF1 HECT-type E3 ubiquitin transferase SMURF1 SMAD ubiquitination regulatory factor 1 SMAD-specific E3 ubiquitin-protein ligase 1
Swiss Prot
Q9HCE7 Human, Q9CUN6 Mouse
Cellular Locus
Cell membrane, Cytoplasm, Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human SMURF1 aa 30-80.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
NIH/3T3 cell lysate, MCF-7 cell lysate, rat kidney tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size:86 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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