MAT2A Rabbit Polyclonal Antibody

• Description:

  Protein expression is regulated by post-transcriptional regulation: in presence of S-adenosyl-L-methionine, METTL16 binds and methylates the first hairpin of the 3'-UTR region of MAT2A mRNA, impairing MAT2A expression . In S-adenosyl-L-methionine-limiting conditions, METTL16 binds the 3'-UTR region of MAT2A mRNA without methylating it due to the lack of a methyl donor, preventing N6-methylation and promoting expression of MAT2A . Consequences of N6-methylation of MAT2A are however subject to discussion: According to a report, N6-methylation of MAT2A affects MAT2A mRNA splicing ). According to a second report, N6-methylation of MAT2A affects MAT2A mRNA stability (By similarity).By similarity1 Publication.

• Product Name Alternative:

  AdoMet synthase 2 antibody AdoMet synthetase 2 antibody AdoMet synthetase antibody AMS 2 antibody AMS2 antibody MAT 2 antibody MAT 2A antibody MAT II antibody MAT-II antibody Mat2a antibody MATA 2 antibody MATA2 antibody MATII antibody Methionine adenosyltransferase 2 antibody Methionine adenosyltransferase antibody Methionine adenosyltransferase II alpha antibody Methionine adenosyltransferase II antibody METK2_HUMAN antibody S adenosylmethionine synthetase gamma form antibody S adenosylmethionine synthetase isoform type 2 antibody S-adenosylmethionine synthase isoform type-2 antibody SAMS 2 antibody SAMS2 antibody

• Abbreviation:

  S-adenosylmethionine synthase isoform type-2 AdoMet synthase 2 Methionine adenosyltransferase 2 MAT 21 Methionine adenosyltransferase II MAT-II

• Swiss Prot:

  P31153 Human, Q3THS6 Mouse, P18298 Rat

• Cellular Locus:

  Nucleoplasm, Cytosol.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human MAT2A aa 70-260.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IHC-P, FC

• Positive Control:

  Rat kidney tissue lysates, rat kidney tissue, human colon tissue, human colon carcinoma tissue, mouse brain tissue, Hela.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:2,000 ;IHC-P: 1:500-1:2,000 ;FC: 1:500-1:1,000

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  44 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4