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MAT2A Rabbit Polyclonal Antibody

CAT: 0992-HA500028Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500028Size:100 µL
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Description
Protein expression is regulated by post-transcriptional regulation: in presence of S-adenosyl-L-methionine, METTL16 binds and methylates the first hairpin of the 3'-UTR region of MAT2A mRNA, impairing MAT2A expression . In S-adenosyl-L-methionine-limiting conditions, METTL16 binds the 3'-UTR region of MAT2A mRNA without methylating it due to the lack of a methyl donor, preventing N6-methylation and promoting expression of MAT2A . Consequences of N6-methylation of MAT2A are however subject to discussion: According to a report, N6-methylation of MAT2A affects MAT2A mRNA splicing ). According to a second report, N6-methylation of MAT2A affects MAT2A mRNA stability (By similarity).By similarity1 Publication.
CAS Number
9007-83-4
Product Name Alternative
AdoMet synthase 2 antibody AdoMet synthetase 2 antibody AdoMet synthetase antibody AMS 2 antibody AMS2 antibody MAT 2 antibody MAT 2A antibody MAT II antibody MAT-II antibody Mat2a antibody MATA 2 antibody MATA2 antibody MATII antibody Methionine adenosyltransferase 2 antibody Methionine adenosyltransferase antibody Methionine adenosyltransferase II alpha antibody Methionine adenosyltransferase II antibody METK2_HUMAN antibody S adenosylmethionine synthetase gamma form antibody S adenosylmethionine synthetase isoform type 2 antibody S-adenosylmethionine synthase isoform type-2 antibody SAMS 2 antibody SAMS2 antibody
Abbreviation
S-adenosylmethionine synthase isoform type-2 AdoMet synthase 2 Methionine adenosyltransferase 2 MAT 21 Methionine adenosyltransferase II MAT-II
Swiss Prot
P31153 Human, Q3THS6 Mouse, P18298 Rat
Cellular Locus
Nucleoplasm, Cytosol.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human MAT2A aa 70-260.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Rat kidney tissue lysates, rat kidney tissue, human colon tissue, human colon carcinoma tissue, mouse brain tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:500-1:2,000 ;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No