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HPD Rabbit Polyclonal Antibody

CAT: 0992-HA500012Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500012Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-Hydroxyphenylpyruvate dioxygenase (HPPD), also known as α-ketoisocaproate dioxygenase (KIC dioxygenase), is an Fe (II)-containing non-heme oxygenase that catalyzes the second reaction in the catabolism of tyrosine - the conversion of 4-hydroxyphenylpyruvate into homogentisate. HPPD also catalyzes the conversion of phenylpyruvate to 2-hydroxyphenylacetate and the conversion of α-ketoisocaproate to β-hydroxy β-methylbutyrate.HPPD is an enzyme that is found in nearly all aerobic forms of life.[In nearly all aerobic beings, 4- Hydroxyphenylpyruvate dioxygenase is responsible for converting 4- Hydroxyphenylpyruvate into homogentisate.This conversion is one of many steps in breaking L-tyrosine into acetoacetate and fumarate.While the overall products of this cycle are used to create energy, plants and higher order eukaryotes utilize HPPD for a much more important reason. In eukaryotes, HPPD is used to regulate blood tyrosine levels, and plants utilize this enzyme to help produce the cofactors plastoquinone and tocopherol which are essential for the plant to survive.
CAS Number
9007-83-4
Product Name Alternative
4 HPPD antibody 4 hydroxyphenylpyruvate dioxygenase antibody 4 hydroxyphenylpyruvic acid oxidase antibody 4-hydroxyphenylpyruvate dioxygenase antibody 4-hydroxyphenylpyruvic acid oxidase antibody 4HPPD antibody GLOD3 antibody glyoxalase domain containing 3 antibody HPD antibody HPPD_HUMAN antibody HPPDase antibody PPD antibody
Abbreviation
4-hydroxyphenylpyruvate dioxygenase 4-hydroxyphenylpyruvic acid oxidase 4HPPD HPD HPPDase
Swiss Prot
P32754 Human, P49429 Mouse, P32755 Rat
Cellular Locus
Cytosol, endoplasmic reticulum membrane, extracellular exosome, golgi membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human HPD aa 1-200.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Rat liver tissue lysate, human kidney tissue lysate, rat kidney tissue, human liver tissue, mouse liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:200-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45/40 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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