HPD Rabbit Polyclonal Antibody

• Description :

  4-Hydroxyphenylpyruvate dioxygenase (HPPD), also known as α-ketoisocaproate dioxygenase (KIC dioxygenase), is an Fe (II)-containing non-heme oxygenase that catalyzes the second reaction in the catabolism of tyrosine - the conversion of 4-hydroxyphenylpyruvate into homogentisate. HPPD also catalyzes the conversion of phenylpyruvate to 2-hydroxyphenylacetate and the conversion of α-ketoisocaproate to β-hydroxy β-methylbutyrate.HPPD is an enzyme that is found in nearly all aerobic forms of life.[In nearly all aerobic beings, 4- Hydroxyphenylpyruvate dioxygenase is responsible for converting 4- Hydroxyphenylpyruvate into homogentisate.This conversion is one of many steps in breaking L-tyrosine into acetoacetate and fumarate.While the overall products of this cycle are used to create energy, plants and higher order eukaryotes utilize HPPD for a much more important reason. In eukaryotes, HPPD is used to regulate blood tyrosine levels, and plants utilize this enzyme to help produce the cofactors plastoquinone and tocopherol which are essential for the plant to survive.

• Product Name Alternative :

  4 HPPD antibody 4 hydroxyphenylpyruvate dioxygenase antibody 4 hydroxyphenylpyruvic acid oxidase antibody 4-hydroxyphenylpyruvate dioxygenase antibody 4-hydroxyphenylpyruvic acid oxidase antibody 4HPPD antibody GLOD3 antibody glyoxalase domain containing 3 antibody HPD antibody HPPD_HUMAN antibody HPPDase antibody PPD antibody

• Abbreviation :

  4-hydroxyphenylpyruvate dioxygenase 4-hydroxyphenylpyruvic acid oxidase 4HPPD HPD HPPDase

• Swiss Prot :

  P32754 Human, P49429 Mouse, P32755 Rat

• Cellular Locus :

  Cytosol, endoplasmic reticulum membrane, extracellular exosome, golgi membrane.

• Host :

  Rabbit

• Species Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein within human HPD aa 1-200.

• Isotype :

  IgG

• Conjugation :

  Non-conjugated

• Type :

  Rabbit polyclonal Antibody

• Applications :

  WB, IHC-P

• Positive Control :

  Rat liver tissue lysate, human kidney tissue lysate, rat kidney tissue, human liver tissue, mouse liver tissue.

• Concentration :

  1 mg/mL

• Dilution :

  WB: 1:500-1:1,000;IHC-P: 1:200-1:1,000

• Purity :

  Immunogen affinity purified.

• Form :

  Liquid

• Buffer :

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight :

  Predicted band size: 45/40 kDa.

• Storage Conditions :

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody :

  No

• CAS Number :

  9007-83-4