NDUFS3 Recombinant Rabbit Monoclonal Antibody [JU10-32]

NDUFS3 Recombinant Rabbit Monoclonal Antibody [JU10-32]

• Description: NDUFS3 (NADH dehydrogenase ubiquinone iron-sulfur protein 3) is one of about 45 subunits comprising complex I of the oxidative phosphorylation electron transport chain. The multisubunit NADH: ubiquinone oxidoreductase (complex I) is the first enzyme complex in the electron transport chain of the mitochondria. NDUFS3 is the last subunit of the seven subunits that make up the core of complex I. Through use of chaotropic agents, complex I can be separated into three different fractions: a flavoprotein fraction, an iron-sulfur protein (IP) fraction, and a hydrophobic protein (HP) fraction. The IP fraction includes NDUFS1-7. NDUFS3 contains a highly conserved casein kinase II phosphorylation site. Mutations in the NDUFS3 gene may cause optic atrophy, Leigh syndrome and complex I deficiency.
• Product Name Alternative: CI 30 antibody CI 30KD antibody CI-30kD antibody Complex I 30KD antibody Complex I 30kDa subunit antibody COMPLEX I, MITOCHONDRIAL RESPIRATORY CHAIN, 30-KD SUBUNIT antibody Complex I-30kD antibody mitochondrial antibody NADH coenzyme Q reductase antibody NADH dehydrogenase (ubiquinone) Fe S protein 3 30kDa antibody NADH dehydrogenase [ubiquinone] iron sulfur protein 3 mitochondrial antibody NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 antibody NADH dehydrogenase ubiquinone 30 kDa subunit antibody NADH-ubiquinone oxidoreductase 30 kDa subunit antibody NADH-Ubiquinone Oxidoreductase Fe-S Protein 3 antibody NDUFS3 antibody NDUS3_HUMAN antibody
• Abbreviation: CI-30kD, NDUFS3
• CAS Number: 9000-83-3
• Swiss Prot: O75489 Human
• Cellular Locus: Mitochondrion inner membrane.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human NDUFS3 aa 215-264 / 264.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell, IF-Tissue, IP
• Positive Control: HepG2 lysates, MCF-7, human colon carcinoma tissue, human kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500;IHC-P: 1:50;IF-Cell: 1:50;IP: 1:10-1:50
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 30 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes