c-Rel Recombinant Rabbit Monoclonal Antibody [JM72-93]

c-Rel Recombinant Rabbit Monoclonal Antibody [JM72-93]

• Description: c-Rel is the cellular cognate of v-Rel, the avian reticuloendotheliosis virus strain T transforming gene. v-Rel encodes a phosphoprotein that is located in the cytoplasm of transformed spleen cells and in the nucleus of non-transformed fibroblasts, in contrast to the c-Rel protein, which is cytoplasmic. c-Rel has been shown to represent a constituent of the κB site binding transcription factor NFκB, which plays a crucial role in the expression of immunoglobulin κ light chain gene. c-Rel is a myeloid checkpoint protein that can be targeted for treating cancer. c-Rel has an important role in B-cell survival and proliferation. The REL gene is amplified or mutated in several human B-cell lymphomas, including diffuse large B-cell lymphoma and Hodgkin's lymphoma.
• Product Name Alternative: Avian reticuloendotheliosis antibody C REL antibody C Rel protein antibody c Rel proto oncogene protein antibody Oncogene REL antibody Oncogene REL avian reticuloendotheliosis antibody Proto-oncogene c-Rel antibody REL antibody REL_HUMAN antibody v rel avian reticuloendotheliosis viral oncogene homolog antibody v rel reticuloendotheliosis viral oncogene homolog antibody V rel reticuloendotheliosis viral oncogene homolog (avian) antibody
• Abbreviation: REL
• CAS Number: 9000-83-3
• Swiss Prot: Q04864 Human
• Cellular Locus: Cytoplasm. Nucleus.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human c-Rel aa 501-550 / 619.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IP
• Positive Control: Human tonsil tissue, human colon cancer tissue, human skin tissue, human placenta tissue, SKOV-3 cell lysate, Raji cell lysate, Daudi cell lysates, Jurkat cell lysate, A431 cell lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 69 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes