Peroxiredoxin 3 Recombinant Rabbit Monoclonal Antibody [JA53-21]

Peroxiredoxin 3 Recombinant Rabbit Monoclonal Antibody [JA53-21]

• Description: Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene. It is a member of the peroxiredoxin family of antioxidant enzymes. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.
• Product Name Alternative: Antioxidant protein 1 antibody AOP 1 antibody AOP-1 antibody AOP1 antibody HBC189 antibody MER5 antibody MGC104387 antibody MGC24293 antibody mitochondrial antibody peroxiredoxin 3 antibody Peroxiredoxin III antibody Peroxiredoxin-3 antibody PRDX3 antibody PRDX3_HUMAN antibody PRO1748 antibody Protein MER5 homolog antibody PRX III antibody Prx-III antibody PRX3 antibody SP 22 antibody SP-22 antibody SP22 antibody Thioredoxin dependent peroxide reductase mitochondrial antibody Thioredoxin-dependent peroxide reductase antibody
• Abbreviation: AOP-1, Prx-III, PRDX3, AOP1
• CAS Number: 9000-83-3
• Swiss Prot: P30048 Human
• Cellular Locus: Mitochondrion.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human Peroxiredoxin 3 aa 207-256 / 256.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC, IP
• Positive Control: MCF-7 cell lysate, A431 cell lysate, Hela, HepG2, MCF-7, human liver tissue, human liver carcinoma tissue, human kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 28 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes