Peroxiredoxin 2 Recombinant Mouse Monoclonal Antibody [7F2-R]

Peroxiredoxin 2 Recombinant Mouse Monoclonal Antibody [7F2-R]

• Description: The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis.
• Product Name Alternative: Epididymis secretory sperm binding protein Li 2a antibody HEL S 2a antibody MGC4104 antibody Natural killer cell enhancing factor B antibody Natural killer cell-enhancing factor B antibody Natural Killer Enhancing Factor B antibody NKEF B antibody NKEF-B antibody NKEFB antibody Peroxiredoxin-2 antibody PRDX 2 antibody PRDX2 antibody PRDX2_HUMAN antibody PrP antibody PRX2 antibody PRXII antibody PTX1 antibody TDPX1 antibody Thiol Specific Antioxidant 1 antibody Thiol specific antioxidant protein antibody Thiol-specific antioxidant protein antibody Thioredoxin Dependent Peroxide Reductase 1 antibody Thioredoxin peroxidase 1 antibody Thioredoxin-dependent peroxide reductase 1 antibody Torin antibody TPX1 antibody TSA antibody
• Abbreviation: NKEF-B, TSA, PRDX2, NKEFB, TDPX1
• CAS Number: 9000-83-3
• Swiss Prot: P32119 Human
• Cellular Locus: Cytoplasm.
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Recombinant full length protein.
• Isotype: IgG1
• Clone: 7F2-R
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: WB
• Positive Control: HEK-293 cell lysate, LNCaP cell lysate, HeLa cell lysate, SH-SY5Y cell lysate, MCF7 cell lysate, HepG2 cell lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:20,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 22 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes