Glucose Transporter GLUT3 Recombinant Rabbit Monoclonal Antibody [JA50-31]

Glucose Transporter GLUT3 Recombinant Rabbit Monoclonal Antibody [JA50-31]

• Description: Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, Insulin stimulates a rapid and dramatic increase in glucose uptake, largely due to the redistribution of the Insulin-inducible glucose transporter, Glut4. In response to Insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to Insulin. Glut2 expression is seen in pancreatic b cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.
• Product Name Alternative: brain antibody FLJ90380 antibody Glucose transporter type 3 antibody Glucose transporter type 3 brain antibody GLUT 3 antibody GLUT-3 antibody GLUT3 antibody GTR3_HUMAN antibody Slc2a3 antibody Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3 antibody Solute carrier family 2, facilitated glucose transporter member 3 antibody
• Abbreviation: GLUT-3, SLC2A3, GLUT3
• CAS Number: 9000-83-3
• Swiss Prot: P11169 Human, P32037 Mouse, Q07647 Rat
• Cellular Locus: Cell membrane. Perikaryon. Cell projection.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human GLUT3 aa 11-60 / 496.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, FC
• Positive Control: HepG2 cell lysate, RAW264.7 cell lysate, C6 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, SH-SY5Y.
• Concentration: 1 mg/mL
• Dilution: WB: 1:5,000 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 54 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes