Glucose Transporter GLUT1 Recombinant Rabbit Monoclonal Antibody [SA0377]

Glucose Transporter GLUT1 Recombinant Rabbit Monoclonal Antibody [SA0377]

• Description: Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene. GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells. This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. One good source of GLUT1 is erythrocyte membranes. GLUT1 accounts for 2 percent of the protein in the plasma membrane of erythrocytes. GLUT1, found in the plasma membrane of erythrocytes, is a classic example of a uniporter. After glucose is transported into the erythrocyte, it is rapidly phosphorylated, forming glucose-6-phosphate, which cannot leave the cell. Mutations in this gene can cause GLUT1 deficiency syndrome 1, GLUT1 deficiency syndrome 2, idiopathic generalized epilepsy 12, dystonia 9, and stomatin-deficient cryohydrocytosis.
• Product Name Alternative: Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity) antibody CSE antibody DYT17 antibody DYT18 antibody DYT9 antibody EIG12 antibody erythrocyte/brain antibody Erythrocyte/hepatoma glucose transporter antibody facilitated glucose transporter member 1 antibody Glucose transporter 1 antibody Glucose transporter type 1 antibody Glucose transporter type 1, erythrocyte/brain antibody GLUT antibody GLUT-1 antibody GLUT1 antibody GLUT1DS antibody GLUTB antibody GT1 antibody GTG1 antibody Gtg3 antibody GTR1_HUMAN antibody HepG2 glucose transporter antibody HTLVR antibody Human T cell leukemia virus (I and II) receptor antibody MGC141895 antibody MGC141896 antibody PED antibody RATGTG1 antibody Receptor for HTLV 1 and HTLV 2 antibody SLC2A1 antibody Solute carrier family 2 (facilitated glucose transporter), member 1 antibody Solute carrier family 2 antibody Solute carrier family 2, facilitated glucose transporter member 1 antibody
• Abbreviation: GLUT-1
• CAS Number: 9000-83-3
• Swiss Prot: P11166 Human, P17809 Mouse, P11167 Rat
• Cellular Locus: Cell membrane, Melanosome
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human GLUT1 aa 443-492 / 492.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
• Positive Control: HeLa cell lysate, PC-12 cell lysate, HeLa, HT-29 cell lysate, HepG2 cell lysate, NIH/3T3 cell lysate, L-929 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, Jurkat, NIH/3T3, C6, human liver tissue, human placenta tissue, human liver carcinoma tissue, human kidney tissue, mouse liver tissue, mouse kidney tissue, HepG2, human lung cancer tissue, human liver tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:5,000-1:50,000 ;IF-Cell: 1:500 ;IHC-P: 1:50-1:5,000 ;IF-Tissue: 1:100 ;FC: 1:500-1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 54 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes