Clathrin heavy chain Recombinant Rabbit Monoclonal Antibody [JA53-02]

Clathrin heavy chain Recombinant Rabbit Monoclonal Antibody [JA53-02]

• Description: Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are englufed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain binding site. The proximal segment of the Clathrin HC protein is essential for interactions between clathrin heavy chains and light chains which result in the formation of the triskelion structure.
• Product Name Alternative: CHC17 antibody Clathrin heavy chain antibody Clathrin heavy chain 1 antibody Clathrin heavy chain 2 antibody Clathrin heavy chain like 1 antibody Clathrin heavy chain on chromosome 17 antibody Clathrin heavy polypeptide antibody CLH 17 antibody CLH 22 antibody CLH-17 antibody CLH1_HUMAN antibody CLH17 antibody CLH22 antibody CLTC antibody CLTCL antibody CLTCL1 antibody CLTCL2 antibody CLTD antibody Hc antibody KIAA0034 antibody
• Abbreviation: CLH-22, CLTCL1, CLH22, CLTCL, CLTD
• CAS Number: 9000-83-3
• Swiss Prot: Q00610 Human, Q68FD5 Mouse, P11442 Rat
• Cellular Locus: Cytoplasmic vesicle membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat, Monkey
• Immunogen: Synthetic peptide within Human Clathrin heavy chain aa 201-250 / 1,675.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: HeLa cell lysate, A431 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, HUVEC cell lysate, SH-SY5Y cell lysate, COS-1 cell lysate, human colon cancer tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 180kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes