Fast Myosin Skeletal Heavy chain Recombinant Rabbit Monoclonal Antibody [PSH05-12]

• Description:

  Myosin-1, also known as 'striated muscle myosin heavy chain 1', is a protein that in humans is encoded by the MYH1 gene. This gene is most highly expressed in fast type IIX/D muscle fibres of vertebrates and encodes a protein found uniquely in striated muscle; it is a class II myosin with a long coiled coil tail that dimerizes and should not be confused with 'Myosin 1' encoded by the MYO1 family of genes (MYO1A-MYO1H). Class I MYO1 genes function in many cell types throughout biology and are single-headed membrane-binding myosins that lack a long coiled coil tail. Myosin is a major contractile protein that converts chemical energy into mechanical energy through the hydrolysis of ATP. Class II Myosins are hexameric proteins composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals, at least ten different myosin heavy chain (MYH) isoforms have been described from striated, smooth, but rarely in non-muscle cells. These isoforms show expression that is spatially and temporally regulated during development.

• Product Name Alternative:

  adult 1 antibody MYH1 antibody MYH1_HUMAN antibody MyHC-2x antibody MyHC-IIx/d antibody Myosin heavy chain 1 antibody Myosin heavy chain 2x antibody Myosin heavy chain antibody Myosin heavy chain IIx/d antibody Myosin-1 antibody skeletal muscle antibody

• Abbreviation:

  MYH1

• Swiss Prot:

  P12882 Human, Q5SX40 Mouse,

• Cellular Locus:

  Cytoplasm, myofibril.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide within human Fast Myosin Skeletal Heavy chain aa

• Isotype:

  IgG

• Clone:

  PSH05-12

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  IHC-P, IF-Tissue

• Positive Control:

  Human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue.

• Concentration:

  1 mg/mL

• Dilution:

  IHC-P: 1:2,000-1:10,000 ;IF-Tissue: 1:400-1:2,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 223 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3