Fast Myosin Skeletal Heavy chain Recombinant Rabbit Monoclonal Antibody [PSH05-12]

Fast Myosin Skeletal Heavy chain Recombinant Rabbit Monoclonal Antibody [PSH05-12]

• Description: Myosin-1, also known as 'striated muscle myosin heavy chain 1', is a protein that in humans is encoded by the MYH1 gene. This gene is most highly expressed in fast type IIX/D muscle fibres of vertebrates and encodes a protein found uniquely in striated muscle; it is a class II myosin with a long coiled coil tail that dimerizes and should not be confused with 'Myosin 1' encoded by the MYO1 family of genes (MYO1A-MYO1H). Class I MYO1 genes function in many cell types throughout biology and are single-headed membrane-binding myosins that lack a long coiled coil tail. Myosin is a major contractile protein that converts chemical energy into mechanical energy through the hydrolysis of ATP. Class II Myosins are hexameric proteins composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals, at least ten different myosin heavy chain (MYH) isoforms have been described from striated, smooth, but rarely in non-muscle cells. These isoforms show expression that is spatially and temporally regulated during development.
• Product Name Alternative: adult 1 antibody MYH1 antibody MYH1_HUMAN antibody MyHC-2x antibody MyHC-IIx/d antibody Myosin heavy chain 1 antibody Myosin heavy chain 2x antibody Myosin heavy chain antibody Myosin heavy chain IIx/d antibody Myosin-1 antibody skeletal muscle antibody
• Abbreviation: MYH1
• CAS Number: 9000-83-3
• Swiss Prot: P12882 Human, Q5SX40 Mouse,
• Cellular Locus: Cytoplasm, myofibril.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human Fast Myosin Skeletal Heavy chain aa
• Isotype: IgG
• Clone: PSH05-12
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IHC-P, IF-Tissue
• Positive Control: Human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue.
• Concentration: 1 mg/mL
• Dilution: IHC-P: 1:2,000-1:10,000 ;IF-Tissue: 1:400-1:2,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 223 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes