NMDAR1 Recombinant Rabbit Monoclonal Antibody [JM11-26]

NMDAR1 Recombinant Rabbit Monoclonal Antibody [JM11-26]

• Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+.Sensitivity to glutamate and channel kinetics depend on the subunit composition.
• Product Name Alternative: GluN1 antibody Glutamate [NMDA] receptor subunit zeta-1 antibody Glutamate receptor ionotropic N methyl D aspartate 1 antibody Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1 antibody glutamate receptor ionotropic, NMDA 1 antibody Grin1 antibody MRD8 antibody N methyl D aspartate receptor antibody N methyl D aspartate receptor channel subunit zeta 1 antibody N methyl D aspartate receptor subunit NR1 antibody N-methyl-D-aspartate receptor subunit NR1 antibody NMD-R1 antibody NMDA 1 antibody NMDA R1 antibody NMDA receptor 1 antibody NMDA1 antibody NMDAR antibody NMDZ1_HUMAN antibody NR1 antibody
• Abbreviation: GluN1, NMD-R1
• CAS Number: 9000-83-3
• Swiss Prot: Q05586 Human, P35438 Mouse, P35439 Rat
• Cellular Locus: Cell membrane, postsynaptic cell membrane, postsynaptic density.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human NMDAR1 aa 870-910.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC, IHC-Fr
• Positive Control: MCF7 cell lysate, human brain tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, N2A, SHG-44, SH-SY5Y, mouse cerebral cortex tissue, rat cerebral cortex tissue, mouse hippocampus tissue, mouse cerebral cortex tissue, rat cerebral cortex tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:5,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:1,000 ;FC: 1:50-1:100 ;IHC-Fr: 1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 105 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes