Vitamin D Binding protein Recombinant Rabbit Monoclonal Antibody [JM10-36]

Vitamin D Binding protein Recombinant Rabbit Monoclonal Antibody [JM10-36]

• Description: Vitamin D-binding protein (DBP), also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene. Vitamin D-binding protein belongs to the albumin gene family, together with human serum albumin and alpha-fetoprotein. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It is able to bind the various forms of vitamin D including ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), the 25-hydroxylated forms (calcifediol), and the active hormonal product, 1,25-dihydroxyvitamin D (calcitriol). The major proportion of vitamin D in blood is bound to this protein. It transports vitamin D metabolites between skin, liver and kidney, and then on to the various target tissues. As Gc protein-derived macrophage activating factor it is a Macrophage Activating Factor (MAF) that has been tested for use as a cancer treatment that would activate macrophages against cancer cells.
• Product Name Alternative: DBP antibody DBP/GC antibody GC antibody Gc globulin antibody Gc-globulin antibody GRD3 antibody Group specific component antibody Group specific component vitamin D binding protein antibody Group-specific component antibody hDBP antibody VDB antibody VDBG antibody VDBP antibody Vitamin D binding alpha globulin antibody Vitamin D-binding protein antibody VTDB_HUMAN antibody
• Abbreviation: DBP, VDB, Gc-MAF, Gc, DBP-maf
• CAS Number: 9000-83-3
• Swiss Prot: P02774 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic pertide within Human Vitamin D Binding protein aa 270-319 / 474.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
• Positive Control: Human lung tissue lysates, Hela, HepG2, SKOV-3, human kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 53 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes