beta 2 Adrenergic Receptor Recombinant Rabbit Monoclonal Antibody [JM102-06]

beta 2 Adrenergic Receptor Recombinant Rabbit Monoclonal Antibody [JM102-06]

• Description: The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline), a hormone and neurotransmitter whose signaling, via adenylate cyclase stimulation through trimeric Gs proteins, increased cAMP, and downstream L-type calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation. The ADRB2 gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
• Product Name Alternative: ADRB2 antibody ADRB2_HUMAN antibody ADRB2R antibody ADRBR antibody Adrenergic beta 2 receptor surface antibody Adrenoceptor beta 2 surface antibody B2AR antibody BAR antibody beta 2 adrenoceptor antibody Beta 2 adrenoreceptor antibody Beta-2 adrenergic receptor antibody Beta-2 adrenoceptor antibody Beta-2 adrenoreceptor antibody BETA2AR antibody Catecholamine receptor antibody OTTHUMP00000160386 antibody
• Abbreviation: ADRB2
• CAS Number: 9000-83-3
• Swiss Prot: P07550 Human, P18762 Mouse, P10608 Rat
• Cellular Locus: Cell membrane, Early endosome.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat, Zebrafish
• Immunogen: Synthetic peptide within Human ADRB2 aa 369-400 / 413.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IP, IF-Cell, FC, IHC-Fr
• Positive Control: A431 cell lysate, human liver tissue lysate, mouse heart tissue lysate, rat heart tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, zebrafish tissue lysates, A431, human liver tissue, human stomach tissue, mouse liver tissue, mouse stomach tissue, rat liver tissue, rat stomach tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:5,000-1:20,000 ;IHC-P: 1:200-1:5,000 ;IP: Use at an assay dependent concentration. ;IF-Cell: 1:100 ;FC: 1:1,000 ;IHC-Fr: 1:500
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 46 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes