PDGF Receptor beta Rabbit Polyclonal Antibody

PDGF Receptor beta Rabbit Polyclonal Antibody

• Description: Platelet-derived growth factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PGDF-AA, PDGF-AB and PDGF-BB. These three isoforms bind with different affinities to two receptor types, PDGFR-α and -β, which are endowed with protein tyrosine kinase domains. PDGFR-α can bind to both A and B subunits of PDGF, while PDGFR- PDGF-AA induces the dimerization of αα and αβ and PDGF-BB induces the formation of three types of PDGF-AB induces dimerization of αα and αβ and PDGF-BB induces the formation of three types A dimlist, αα, αβ and ββ. Translocation of the PDGFR-β gene with the Tel gene is linked to chronic myelomonocytic leukemia (CMML), a myelodysplastic syndrome, and demonstrate the oncogenic potential of the PDGF receptors.
• Product Name Alternative: Beta platelet derived growth factor receptor antibody Beta-type platelet-derived growth factor receptor antibody CD 140B antibody CD140 antigen-like family member B antibody CD140b antibody CD140b antigen antibody IBGC4 antibody IMF1 antibody JTK12 antibody OTTHUMP00000160528 antibody PDGF R beta antibody PDGF-R-beta antibody PDGFR 1 antibody PDGFR antibody PDGFR beta antibody PDGFR1 antibody PDGFRB antibody PGFRB_HUMAN antibody Platelet derived growth factor receptor 1 antibody Platelet derived growth factor receptor beta antibody Platelet derived growth factor receptor beta polypeptide antibody
• Abbreviation: PDGF-R-beta, PDGFR-beta, PDGFR-1, PDGFRB, PDGFR, PDGFR1
• CAS Number: 9007-83-4
• Swiss Prot: P09619 Human, P05622 Mouse, Q05030 Rat
• Cellular Locus: Cell membrane, Lysosome lumen.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human PDGF Receptor beta aa 180-222.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: Hela, HepG2, MCF-7, human spleen tissue, mouse brain tissue, NIH-3T3.
• Concentration: 1 mg/mL
• Dilution: IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;WB: 1:500
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 124 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No