HRP Conjugated GAPDH Recombinant Rabbit Monoclonal Antibody [JF81-04]

• Description:

  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), also called uracil DNA glycosylase, catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. While GAPDH has long been recognized as playing an integral role in glycolysis, additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Expression of GAPDH is upregulated in liver, lung and prostate cancers. GAPDH translocates to the nucleus during apoptosis. GAPDH complexes with neuronal proteins implicated in human neuro-degenerative disorders including the β-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins.

• Product Name Alternative:

  38 kDa BFA-dependent ADP-ribosylation substrate antibody aging associated gene 9 protein antibody Aging-associated gene 9 protein antibody BARS-38 antibody cb609 antibody EC 1.2.1.12 antibody Epididymis secretory sperm binding protein Li 162eP antibody G3P_HUMAN antibody G3PD antibody G3PDH antibody GAPD antibody GAPDH antibody Glyceraldehyde 3 phosphate dehydrogenase antibody Glyceraldehyde-3-phosphate dehydrogenase antibody HEL-S-162eP antibody KNC-NDS6 antibody MGC102544 antibody MGC102546 antibody MGC103190 antibody MGC103191 antibody MGC105239 antibody MGC127711 antibody MGC88685 antibody OCAS, p38 component antibody OCT1 coactivator in S phase, 38-KD component antibody peptidyl cysteine S nitrosylase GAPDH antibody Peptidyl-cysteine S-nitrosylase GAPDH antibody wu:fb33a10 antibody

• Abbreviation:

  GAPDH

• Swiss Prot:

  P04406 Human, P16858 Mouse, P04797 Rat

• Cellular Locus:

  Cytoplasm, Nucleus, Membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat, Monkey, Chicken, Fish

• Immunogen:

  Recombinant full length protein of Human GAPDH aa 1-335 / 335.

• Isotype:

  IgG

• Conjugation:

  HRP-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB

• Positive Control:

  HeLa cell lysate, L-929 cell lysate, RAW264.7 cell lysate, C6 cell lysate, COS-1 cell lysate, rat heart tissue lysate.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:50,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol.

• Molecular Weight:

  Predicted band size: 36 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3