Midkine Recombinant Rabbit Monoclonal Antibody [JF096-5]

Midkine Recombinant Rabbit Monoclonal Antibody [JF096-5]

• Description: Midkine, or MK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MK expression is tightly regulated during embryonic development by steroid receptors of the retinoic acid superfamily. The mature human MK protein is 118 amino acids in length and contains five intrachain disulfide bonds. MK is a non-glycosylated protein that shows greater than 87% identity between human and mouse. The carboxy-terminus of MK contains the principle heparin-binding site and the molecule’s neurite-promoting sequences; both the amino- and carboxy-terminal sequences are required for the molecule’s neurotrophic properties. An association between overexpression of MK and colon adenocarcinoma has been shown in families suffering from familial polyposis. In addition, MK functions to enhance the activity of plasminogen activator (PA).
• Product Name Alternative: Amphiregulin associated protein antibody Amphiregulin-associated protein antibody ARAP antibody FLJ27379 antibody Mdk antibody Midgestation and kidney protein antibody Midkine antibody MK 1 antibody MK antibody MK_HUMAN antibody MK1 antibody NEGF 2 antibody NEGF2 antibody Neurite growth promoting factor 2 antibody Neurite outgrowth promoting protein antibody Neurite outgrowth-promoting factor 2 antibody Neurite outgrowth-promoting protein antibody Retinoic acid inducible factor antibody
• Abbreviation: MK, ARAP, MDK
• CAS Number: 9000-83-3
• Swiss Prot: P21741 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human Midkine aa 100-143 / 143.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IP
• Positive Control: HepG2 cell lysate, SH-SY5Y cell lysate, U-2 OS cell lysate, human liver tissue, human pancreas tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 16 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes