Laminin 2 alpha Recombinant Rabbit Monoclonal Antibody [PSH0-94]

Laminin 2 alpha Recombinant Rabbit Monoclonal Antibody [PSH0-94]

• Description: Laminin subunit alpha-2 is a protein that in humans is encoded by the LAMA2 gene. Laminin, an extracellular matrix protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.
• Product Name Alternative: LAMA 2 antibody LAMA2 antibody LAMA2_HUMAN antibody Laminin alpha 2 (merosin congenital muscular dystrophy) antibody Laminin alpha 2 antibody Laminin alpha 2 chain antibody Laminin alpha 2 subunit antibody Laminin M antibody Laminin M chain antibody Laminin subunit alpha-2 antibody Laminin-12 subunit alpha antibody Laminin-2 subunit alpha antibody Laminin-4 subunit alpha antibody LAMM antibody Merosin heavy chain antibody
• Abbreviation: LAMA2, LAMM
• CAS Number: 9000-83-3
• Swiss Prot: P24043 Human, Q60675 Mouse,
• Cellular Locus: Secreted, extracellular space, extracellular matrix, basement membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human Laminin 2 alpha 1,151-1,400 / 3,122.
• Isotype: IgG
• Clone: PSH0-94
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Tissue
• Positive Control: Mouse heart tissue lysate, rat heart tissue lysate, mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, human heart tissue, mouse heart tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Tissue: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 344 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes