Doublecortin Recombinant Rabbit Monoclonal Antibody [JJ0959]

Doublecortin Recombinant Rabbit Monoclonal Antibody [JJ0959]

• Description: Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, resulting in severe mental retardation. Genetic analysis identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 shows sequence homology to β-subunits of heterotrimeric G proteins. Doublecortin contains a consensus Abl phosphorylation site, and it has some sequence homology to a predicted kinase protein. Both proteins are highly expressed in developing brain, suggesting that they may be involved in a signal transduction pathway that is crucial to brain development.
• Product Name Alternative: DBCN antibody Dbct antibody DC antibody DCX antibody DCX_HUMAN antibody Doublecortex antibody Doublin antibody FLJ51296 antibody Lis X antibody Lis-X antibody Lissencephalin X antibody Lissencephalin-X antibody Lissencephaly X linked antibody Lissencephaly X linked doublecortin antibody LISX antibody Neuronal migration protein doublecortin antibody OTTHUMP00000023859 antibody OTTHUMP00000023860 antibody OTTHUMP00000216315 antibody OTTHUMP00000216316 antibody SCLH antibody XLIS antibody
• Abbreviation: Lis-X, DCX
• CAS Number: 9000-83-3
• Swiss Prot: O43602 Human, O88809 Mouse, Q9ESI7 Rat
• Cellular Locus: Cytoplasm, Cell projection.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Doublecortin aa 22-71 / 365.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB
• Positive Control: Neuro-2a cell lysate, human brain tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, HepG2.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:5,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 41 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes