Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949]

Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949]

• Description: Insulin degrading enzyme (IDE), also known as insulinase, insulin protease or insulysin, cleaves the peptide hormone insulin with consequences for insulin response and resistance. IDE is a highly conserved thiol metalloprotease with ubiquitous expression including the brain. Since its discovery, IDE has been shown to degrade a variety of bioactive peptides. Recently the finding that IDE clears intracellular and extracellular amyloid products has spurred research into the link between IDE function and human neurodegenerative disease such as Alzheimer’s.
• Product Name Alternative: Abeta-degrading protease antibody FLJ35968 antibody Ide antibody IDE_HUMAN antibody Insulin protease antibody Insulin-degrading enzyme antibody Insulinase antibody Insulysin antibody OTTHUMP00000020097 antibody
• Abbreviation: Insulinase, IDE
• CAS Number: 9000-83-3
• Swiss Prot: P14735 Human, Q9JHR7 Mouse, P35559 Rat
• Cellular Locus: Cytoplasm, Cell membrane, Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat, Zebrafish
• Immunogen: Recombinant protein within Human Insulin degrading enzyme aa 1-106 / 1019.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: Zebrafish tissue lysate, Hela cell lysate, K562 cell lysate, human liver carcinoma tissue, human colon carcinoma tissue, human stomach carcinoma tissue, mouse colon tissue, hybrid fish (crucian-carp) heart tissue lysates.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 118 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes