Ubiquitin D Recombinant Rabbit Monoclonal Antibody [JJ084-09]

Ubiquitin D Recombinant Rabbit Monoclonal Antibody [JJ084-09]

• Description: FAT10, also designated Ubiquitin D or Diubiquitin, is a 165 amino acid protein encoded in the major histocompatibility complex (MHC) that consists of two domains which share significant homology with ubiquitin. Each domain contains two cysteines, along with a free C-terminal diglycine motif required for FAT10 conjugate formation. FAT10 is inducible by interferon-g and tumor necrosis factor a (TNF?). The FAT10 protein interacts with MAD2, a component of the spindle checkpoint, and plays a role in antigen presentation, cytokine response, apoptosis and mitosis. It may also regulate cell growth during dendritic cell or B cell activation and development. FAT10 mRNA is expressed mainly in some dendritic cells and lymphoblastoid lines and in other specific cells subsequent to interferon-g induction. The human FAT10 gene, designated UBD, maps to chromosome 6p21.3 and is overexpressed in the tumors of various epithelial cancers.
• Product Name Alternative: Diubiquitin antibody FAT10 antibody GABBR1 antibody UBD 3 antibody Ubd antibody UBD_HUMAN antibody Ubiquitin D antibody Ubiquitin like protein FAT10 antibody Ubiquitin-like protein FAT10 antibody
• Abbreviation: UBD
• CAS Number: 9000-83-3
• Swiss Prot: O15205 Human, P63072 Mouse, Q921A3 Rat
• Cellular Locus: Nucleus, Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Ubiquitin D aa 114-158 / 165.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: HepG2 cell lysate, Hela cell lysate, SK-Br-3 cell lysate, K562 cell lysate, Hela, F9, HepG2, human kidney tissue, mouse kidney tissue, rat kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:100-1:500 ;IHC-P: 1:200-1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 18 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes