A-RAF Recombinant Rabbit Monoclonal Antibody [JJ08-68]

A-RAF Recombinant Rabbit Monoclonal Antibody [JJ08-68]

• Description: Serine/threonine-protein kinase A-Raf or simply A-Raf is an enzyme that in humans is encoded by the ARAF gene. A-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases. Compared to the other members of this family (Raf-1 and B-Raf), very little is known about A-Raf. It seems to share many of the properties of the other isoforms, but its biological functions are not as thoroughly researched. All three Raf proteins are involved in the MAPK signaling pathway. There are several ways A-Raf is different from the other Raf kinases. A-Raf is the only steroid hormone-regulated Raf isoform. In addition, the A-Raf protein has amino acid substitutions in a negatively charged region upstream of the kinase domain (N-region). This could be responsible for its low basal activity.
• Product Name Alternative: A raf 1 antibody A Raf proto oncogene serine/threonine protein kinase antibody ARAF 1 antibody Araf antibody ARaf proto oncogene serine/threonine protein kinase antibody ARAF_HUMAN antibody ARAF1 antibody Oncogene Araf1 antibody Oncogene PKS2 antibody PKS 2 antibody PKS antibody PKS2 antibody Proto oncogene Pks antibody Proto-oncogene A-Raf antibody Proto-oncogene A-Raf-1 antibody Proto-oncogene Pks antibody RAFA 1 antibody RAFA1 antibody Ras binding protein DA Raf antibody Serine/threonine-protein kinase A-Raf antibody v raf murine sarcoma 3611 viral oncogene homolog antibody v raf murine sarcoma 3611 viral oncogene homolog 1 antibody v raf oncogene homolog 1 (murine sarcoma 3611 virus) antibody
• Abbreviation: ARAF
• CAS Number: 9000-83-3
• Swiss Prot: P10398 Human, P04627 Mouse
• Cellular Locus: Cytosol.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Recombinant protein within Human A-RAF aa 146-310 / 606.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
• Positive Control: Hela cell lysate, A431 cell lysate, Hela, A431, NIH/3T3, human kidney tissue, human breast carcinoma tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 68 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes