14-3-3 epsilon Recombinant Rabbit Monoclonal Antibody [JJ08-40]

14-3-3 epsilon Recombinant Rabbit Monoclonal Antibody [JJ08-40]

• Description: 14-3-3 protein epsilon is a protein that in humans is encoded by the YWHAE gene. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer, and microdeletions associated with Miller–Dieker syndrome.
• Product Name Alternative: 14 3 3 E antibody 14 3 3 epsilon antibody 14 3 3E antibody 14-3-3 protein epsilon antibody 14-3-3E antibody 1433E_HUMAN antibody Epididymis luminal protein 2 antibody FLJ45465 antibody FLJ53559 antibody HEL2 antibody KCIP 1 antibody KCIP1 antibody MDCR antibody MDS antibody Mitochondrial import stimulation factor L subunit antibody Protein kinase C inhibitor protein1 antibody Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, epsilon antibody Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, epsilon polypeptide antibody Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide antibody YWHAE antibody
• Abbreviation: 14-3-3E, YWHAE
• CAS Number: 9000-83-3
• Swiss Prot: P62258 Human, P62259 Mouse, P62260 Rat
• Cellular Locus: Nucleus, Cytoplasm, Melanosome.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human 14-3-3 epsilon aa 51-100.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
• Positive Control: 293T cell lysate, SH-SY5Y cell lysate, Hela, SH-SY5Y, NIH/3T3, mouse placenta tissue, human colon carcinoma tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:10-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 29 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes