Phospholipase C beta 3/PLCB3 Recombinant Rabbit Monoclonal Antibody [JE39-14]

Phospholipase C beta 3/PLCB3 Recombinant Rabbit Monoclonal Antibody [JE39-14]

• Description: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 is an enzyme that in humans is encoded by the PLCB3 gene. The gene codes for the enzyme phospholipase C β3. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11, as well as G-beta gamma subunits. PLCB3 has been shown to interact with Sodium-hydrogen exchange regulatory cofactor 2.
• Product Name Alternative: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3 antibody 1-phosphatidylinositol-4 antibody 5-bisphosphate phosphodiesterase beta-3 antibody Phosphoinositide phospholipase C antibody Phosphoinositide phospholipase C-beta-3 antibody Phospholipase C beta 3 antibody Phospholipase C beta 3 (phosphatidylinositol specific) antibody Phospholipase C-beta-3 antibody PLC beta 3 antibody PLC-beta-3 antibody Plcb3 antibody PLCB3_HUMAN antibody PLCB3 antibody
• Abbreviation: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Phosphoinositide phospholipase C-beta-3 Phospholipase C-beta-3 (PLC-beta-3) PLCB3
• CAS Number: 9000-83-3
• Swiss Prot: Q01970 Human
• Cellular Locus: Cytoplasm. Membrane. Nucleus.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human Phospholipase C beta 3/PLCB3 aa 1,161-1,210 / 1,234.
• Isotype: IgG
• Clone: JE39-14
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: K-562 cell lysate, MCF7 cell lysate, HeLa cell lysate, HCT 116 cell lysate, SH-SY5Y cell lysate, human small intestine tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:2,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 139 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes