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Insulin Recombinant Rabbit mAb

CAT: 0384-BS49189-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS49189-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10
Swiss Prot
P01308
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human Insulin
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
12 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Host or Source
Rabbit

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