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MATER Rabbit Polyclonal Antibody

CAT: 0992-ER50101Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER50101Size:100 µL
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Description
NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals. Conserved oocyte-specific expression of NLRP5 is consistent among many mammalian species. As a member of the subcortical maternal complex (SCMC), it plays an essential role for zygotes to progress beyond the first embryonic cell divisions. NLRP5 also localizes to the nuclear envelope and mitochondria in germinal vesicle oocytes, suggesting a possible role in mitochondrial function.
CAS Number
9007-83-4
Product Name Alternative
CLR19.8 antibody MATER antibody Mater protein homolog antibody Maternal antigen that embryos require antibody NACHT, leucine rich repeat and PYD containing 5 antibody NACHT, LRR and PYD domains-containing protein 5 antibody NALP5_HUMAN antibody NLR family, pyrin domain containing 5 antibody NLRP5 antibody Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 antibody PAN11 antibody PYPAF8 antibody
Abbreviation
MATER, NALP5
Swiss Prot
P59047 Human
Cellular Locus
Cytoplasm, nucleus, mitochondrion.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within mouse MATER aa 1,114-1,163 / 1,163 mouse (ID: Q9R1M5).
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell
Positive Control
Mouse blastocyst, mouse embryo.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
134 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No