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CBR1 Rabbit Polyclonal Antibody

CAT: 0992-ER2001-45Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER2001-45Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol . Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
CAS Number
9007-83-4
Product Name Alternative
15 hydroxyprostaglandin dehydrogenase [NADP+] antibody 15-hydroxyprostaglandin dehydrogenase [NADP+] antibody Carbonyl reductase [NADPH] 1 antibody Carbonyl Reductase 1 antibody CBR 1 antibody CBR1 antibody CBR1_HUMAN antibody CRN antibody NADPH dependent carbonyl reductase 1 antibody NADPH-dependent carbonyl reductase 1 antibody Prostaglandin 9 ketoreductase antibody Prostaglandin 9-ketoreductase antibody Prostaglandin E (2) 9 reductase antibody Prostaglandin-E (2) 9-reductase antibody SDR21C1 antibody
Abbreviation
Carbonyl reductase [NADPH] 1,15-hydroxyprostaglandin dehydrogenase 20-beta-hydroxysteroid dehydrogenase NADPH-dependent carbonyl reductase 1 Prostaglandin 9-ketoreductase1 PG-9-KR1 Prostaglandin-E (2) 9-reductaseBy similarity Short chain dehydrogenase/reductase family 21C member 1
Swiss Prot
P16152 Human, P47727 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Synthetic peptide within human CBR1 aa 220-277.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
SKBR-3 cell lysate, A549 cell lysate, Siha cell lysate, rat testis tissue, human liver carcinoma tissue, human skin tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:200-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
30 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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