Products for Research Use Only
RegisterLogin

Dysbindin Rabbit Polyclonal Antibody

CAT: 0992-ER2001-26Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-ER2001-26Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
CAS Number
9007-83-4
Product Name Alternative
DTBP1_HUMAN antibody DTNBP1 antibody Dysbindin antibody Dysbindin-1 antibody Dystrobrevin binding protein 1 antibody Dystrobrevin-binding protein 1 antibody Hermansky Pudlak syndrome 7 protein antibody Hermansky-Pudlak syndrome 7 protein antibody HPS7 antibody HPS7 protein antibody
Abbreviation
Dysbindin.Biogenesis of lysosome-related organelles complex 1 subunit 8 BLOC-1 subunit 8 DTNBP1 Dysbindin-1 Dystrobrevin-binding protein 1 Hermansky-Pudlak syndrome 7 protein HPS7 protein
Swiss Prot
Q96EV8 Human, Q91WZ8 Mouse, Q5M834 Rat
Cellular Locus
Cell junction, Cell membrane, Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Membrane, Nucleus, Postsynaptic cell membrane, Synapse
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within human Dysbindin aa 150-351.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Daudi cell lysate, MCF-7 cell lysate, HL-60 cell lysate, human spleen tissue, mouse testis tissue, MCF-7.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 40 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
ER1901-73GABARAPL2 Rabbit Polyclonal Antibody
ER2001-53Transferrin Rabbit Polyclonal Antibody
ER1802-12LSD1 Rabbit Polyclonal Antibody
HA500270AIM2 Rabbit Polyclonal Antibody
HA500595TMEM184A Rabbit polyclonal Antibody
HA500594HERC6 Rabbit polyclonal Antibody
HA500591COL4A3 Rabbit polyclonal Antibody
HA500589BAHD1 Rabbit polyclonal Antibody
HA500587OTULIN Rabbit polyclonal Antibody
HA500572ZDHHC24 Rabbit polyclonal Antibody

Alternative Products

CatalogName
NBP3-30425Rabbit Polyclonal Dysbindin Antibody
GTR18308181Dysbindin Rabbit Polyclonal Antibody
TA362597Dysbindin (DTNBP1) Rabbit Polyclonal Antibody
GTR18106951-01Dysbindin 1 Rabbit Polyclonal Antibody
GTR18594294Dysbindin/DTNBP1 Rabbit Polyclonal Antibody
GTR18594289Dysbindin/DTNBP1 Rabbit Polyclonal Antibody (HRP)
GTR18762161Dysbindin/DTNBP1 Rabbit Polyclonal Antibody (Fluoro550)
GTR18762159Dysbindin/DTNBP1 Rabbit Polyclonal Antibody (Fluoro647)
GTR18594293Dysbindin/DTNBP1 Rabbit Polyclonal Antibody (Biotin)
GTR18594291Dysbindin/DTNBP1 Rabbit Polyclonal Antibody (FITC)

Popular Products