CD180 Rabbit Polyclonal Antibody

CAT: 0992-ER2001-06Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-ER2001-06Size:100 µL
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Description
CD180 antigen is a protein that in humans is encoded by the CD180 gene. CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. It is also known by the archaic terms Bgp-95 and RP105, for the founding designations following discovery in humans (1988) and mice (1994), respectively. CD180 is expressed on antigen presenting cells including B cells and dendritic cells. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, CD180/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). CD180/MD-1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. Recently, CD180 has been demonstrated to be involved in the survival and prognosis of B-cell chronic lymphocytic leukemia.
CAS Number
9007-83-4
Product Name Alternative
CD180 antibody CD180 antigen antibody CD180_HUMAN antibody F630107B15 antibody LY64 antibody Ly78 antibody Lymphocyte antigen 64 antibody lymphocyte antigen 64 radioprotective 105kDa antibody lymphocyte antigen-64, radioprotective, 105kDa antibody MGC126233 antibody MGC126234 antibody Radioprotective 105 kDa protein antibody RP105 antibody
Abbreviation
CD180
Swiss Prot
Q99467 Human, Q62192 Mouse
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human CD180 aa 370-580.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Daudi cell lysate, rat spleen tissue lysate, mouse spleen tissue lysate, rat spleen tissue, human spleen tissue, mouse spleen tissue, Daudi.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 74 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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