Optineurin Rabbit Polyclonal Antibody

Optineurin Rabbit Polyclonal Antibody

• Description: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
• Product Name Alternative: 14.7K interacting protein antibody Ag9 C5 antibody ALS12 antibody E3 14.7K interacting protein antibody E3-14.7K-interacting protein antibody FIP 2 antibody FIP-2 antibody FIP2 antibody Glaucoma 1 open angle E (adult onset) antibody Glaucoma 1 open angle E antibody GLC1E antibody HIP 7 antibody HIP-7 antibody HIP7 antibody Huntingtin interacting protein 7 antibody Huntingtin interacting protein HYPL antibody Huntingtin interacting protein L antibody Huntingtin yeast partner L antibody Huntingtin-interacting protein 7 antibody Huntingtin-interacting protein L antibody HYPL antibody Injury inducible protein I 55 antibody NEMO related protein antibody NEMO-related protein antibody NRP antibody Optic neuropathy inducing protein antibody Optic neuropathy-inducing protein antibody Optineurin antibody OPTN antibody OPTN_HUMAN antibody TFIIIA IntP antibody TFIIIA-IntP antibody Transcription factor IIIA interacting protein antibody Transcription factor IIIA-interacting protein antibody Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains antibody
• Abbreviation: OPTN
• CAS Number: 9007-83-4
• Swiss Prot: Q96CV9 Human
• Cellular Locus: Golgi apparatus, trans-Golgi network, Recycling endosome, perinuclear region, autophagosome, Cytoplasmic vesicle.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within human optineurin aa 1-40.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, FC
• Positive Control: A431 cell lysates, human liver tissue, human kidney tissue, human placenta tissue, MCF-7.
• Concentration: 1 mg/mL
• Dilution: WB:1:500-1:1,000 ;FC:1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 66 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No