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L1CAM Rabbit Polyclonal Antibody

CAT: 0992-0805-5Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-0805-5Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The neural cell adhesion molecule L1 (NCAM-L1) is an immunoglobulin superfamily adhesion molecule that is critical for neural development, involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Defects in L1CAM are the cause of hydrocephalus due to stenosis of the aqueduct of Sylvius (HSAS). Hydrocephalus is a condition in which abnormal accumulation of cerebrospinal fluid in the brain causes increased intracranial pressure inside the skull. Defects in L1CAM are also the cause of mental retardation, aphasia, shuffling gait, and adducted thumbs syndrome (MASA), a X-linked disorder.
CAS Number
9007-83-4
Product Name Alternative
Antigen identified by monoclonal antibody R1 antibody CAML1 antibody CD171 antibody CD171 antigen antibody HSAS antibody HSAS1 antibody Hyd antibody L1 antibody L1 cell adhesion molecule antibody L1-NCAM antibody L1cam antibody L1CAM_HUMAN antibody MASA antibody MIC5 antibody N CAML1 antibody N-CAM-L1 antibody NCAM-L1 antibody NCAML1 antibody Nerve-growth factor-inducible large external glycoprotein antibody Neural cell adhesion molecule L1 antibody NILE antibody OTTHUMP00000025992 antibody S10 antibody SPG1 antibody
Abbreviation
L1CAM, CAML1, MIC5
Swiss Prot
P32004 Human, P11627 Mouse, Q05695 Rat
Cellular Locus
Cell membrane, Cell projection, Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human L1CAM aa 1,208-1,257 / 1,257.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
A375 cell lysate, A549 cell lysate, HeLa cell lysate, human brain tissue lysate, rat brain tissue lysate, mouse brain tissue lysate, A375, 293T, Hela, human breast cancer tissue, human kidney tissue, mouse kidney tissue, SHG-44.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:600 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 140 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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