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PICK1 Rabbit Polyclonal Antibody

CAT: 0992-ER1902-97Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1902-97Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
CAS Number
9007-83-4
Product Name Alternative
dJ1039K5 antibody MGC15204 antibody OTTHUMP00000028509 antibody PICK 1 antibody Pick1 antibody PICK1_HUMAN antibody PRKCA binding protein antibody PRKCA-binding protein antibody PRKCABP antibody Protein interacting with C kinase 1 antibody Protein interacting with PRKCA antibody Protein interacting with PRKCA 1 antibody Protein kinase C alpha binding protein antibody Protein kinase C-alpha-binding protein antibody Protein that interacts with C kinase 1 antibody
Abbreviation
PICK1
Swiss Prot
Q9NRD5 Human, Q62083 Mouse, Q9EP80 Rat
Cellular Locus
Cytoskeleton, perinuclear region, membrane, postsynaptic density, synaptosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within rat PICK1 aa 280-330.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
SH-SY5Y cell lysate, 293 cell lysate, F9, MCF-7, rat brain tissue, human colon tissue, mouse brain tissue, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000;IF-Cell:1:50-1:100;IHC-P:1:50-1:200;FC:1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size 47/40 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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