Rab11-FIP3 Rabbit Polyclonal Antibody

Rab11-FIP3 Rabbit Polyclonal Antibody

• Description: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track).
• Product Name Alternative: EF hands containing Rab interacting protein antibody Eferin antibody Rab11 family interacting protein 3 antibody RAB11FIP3 antibody RFIP3 antibody
• Abbreviation: Rab11fip3
• CAS Number: 9007-83-4
• Swiss Prot: O75154 Human, Q8CHD8 Mouse
• Cellular Locus: Recycling endosome membrane, centrosome, Cleavage furrow, Midbody.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within mouse FIP3 aa 543-592 / 1,047.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P
• Positive Control: MCF-7 cell lysates, mouse liver tissue, mouse kindey tissue.
• Concentration: 1 mg/mL
• Dilution: WB:1:500-1:2,000;IHC-P:1:50-1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size 82/119 kDa.
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No