Ki67 Rabbit Polyclonal Antibody
CAT:
992-ER1902-75
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Ki67 Rabbit Polyclonal Antibody
- Description: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
- Product Name Alternative: Antigen identified by monoclonal antibody Ki 67 antibody Antigen identified by monoclonal antibody Ki-67 antibody Antigen KI-67 antibody Antigen KI67 antibody Antigen Ki67 antibody KI67_HUMAN antibody KIA antibody Marker of proliferation Ki-67 antibody MIB 1 antibody MIB antibody MKI67 antibody PPP1R105 antibody Proliferation marker protein Ki-67 antibody Proliferation related Ki 67 antigen antibody Protein phosphatase 1 regulatory subunit 105 antibody RP11-380J17.2 antibody
- Abbreviation: Proliferation marker protein Ki-6,Antigen identified by monoclonal antibody Ki-67,Antigen KI-67,Antigen Ki67,MKI67
- CAS Number: 9007-83-4
- Swiss Prot: P46013 Human
- Cellular Locus: Chromosome, Nucleus
- Host: Rabbit
- Species Reactivity: Human
- Immunogen: Synthetic peptide within Human Ki67 aa 1,949-1,998 / 3,256.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB, IHC-P, IF-Cell
- Positive Control: HepG2 cell lysates, A549, human colon cancer tissue.
- Concentration: 1 mg/mL
- Dilution: WB: 1:10,000-1:50,000 ;IHC-P: 1:200-1:1,000 ;IF-Cell: 1:50-1:200
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size 359 kDa.
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No