CDK5RAP3 Rabbit Polyclonal Antibody
CAT:
992-ER1902-72
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK5RAP3 Rabbit Polyclonal Antibody
- Description: Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation . Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation . Also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint. Through its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation . May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress . May also play a role in the rupture of the nuclear envelope during apoptosis . May regulate MAPK14 activity by regulating its dephosphorylation by PPM1D/WIP1
- Product Name Alternative: C53 antibody CDK5 activator binding protein C53 antibody CDK5 activator-binding protein C53 antibody CDK5 regulatory subunit associated protein 3 antibody CDK5 regulatory subunit-associated protein 3 antibody Cdk5rap3 antibody CK5P3_HUMAN antibody HSF 27 antibody HSF27 antibody IC53 antibody Ischemic heart CDK5 activator binding protein C53 antibody LXXLL/leucine zipper containing ARFbinding protein antibody LZAP antibody MST016 antibody OK/SW cl.114 antibody PP1553 antibody Protein HSF-27 antibody
- Abbreviation: CDK5 regulatory subunit-associated protein ,CDK5 activator-binding protein C53 LXXLL/leucine-zipper-containing ARF-binding protein Protein HSF-27 CDK5RAP3
- CAS Number: 9007-83-4
- Swiss Prot: Q96JB5 Human
- Cellular Locus: Cytoplasm, Cytoskeleton, Nucleus.
- Host: Rabbit
- Species Reactivity: Human
- Immunogen: Recombinant protein within Human CDK5RAP3 aa 296-506 / 506.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB, IF-Cell, FC
- Positive Control: MCF-7 cell lysates, LOVO, PC-3M, SHSY5Y.
- Concentration: 1 mg/mL
- Dilution: WB: 1:500;IF-Cell: 1:50-1:200;FC: 1:50-1:100
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size 57 kDa.
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No