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ATP8A1 Rabbit Polyclonal Antibody

CAT: 0992-ER1902-61Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1902-61Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.
CAS Number
9007-83-4
Product Name Alternative
Phospholipid-transporting ATPase IA antibody ATPase class I type 8A member 1 antibody Chromaffin granule ATPase II antibody P4-ATPase flippase complex alpha subunit ATP8A1 antibody ATP8A1 antibody
Abbreviation
Phospholipid-transporting ATPase IA,ATPase class I type 8A member 1 Chromaffin granule ATPase II P4-ATPase flippase complex alpha subunit ATP8A1,ATP8A1
Swiss Prot
Q9Y2Q0 Human, A0A8I5ZXX6 Rat
Cellular Locus
Cell membrane, Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Membrane.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within Human ATP8A1 aa 410-637 / 1,164.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
MCF-7 cell lysate, rat brain tissue lysate, MCF-7.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 131 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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