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SPATA13 Rabbit Polyclonal Antibody

CAT: 0992-ER1902-32Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1902-32Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
CAS Number
9007-83-4
Product Name Alternative
APC-stimulated guanine nucleotide exchange factor 2 antibody ARHGEF29 antibody Asef2 antibody FLJ31208 antibody RP11-307N16.3 antibody Spata13 antibody Spermatogenesis-associated protein 13 antibody SPT13_HUMAN antibody
Abbreviation
Spermatogenesis-associated protein 13 APC-stimulated guanine nucleotide exchange factor 2 SPATA13 Asef2
Swiss Prot
Q96N96 Human, Q5DU57 Mouse
Cellular Locus
Cell membrane, Cell projection, Cytoplasm, Membrane.
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein within Human SPATA13 aa 423-572 / 652.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Rat kidney tissue lysates, rat testis tissue, human colon cancer tissue, human kidney tissue, SHSY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 75 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No